United States

% Carbapenem-Resistant Enterobacteriaceae (CRE) in 2019
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2.4%576 Resistant / 24152 Tested

Prevention Progress for C. Difficile Infections
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0.52This value in SIR in 2020 is 48% less than the 2015 national baseline.

Hospital Antibiotic Stewardship Implementation Rate
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91%National implementation rate in 2020


United States' Healthcare-Associated Infection (HAI) Standardized Infection Ratio (SIR) of 0.52 for C. difficile is more than the national SIR of 0.48 for C. difficile in 2020.

United States reported 2.4% antibiotic resistance for CRE in 2019, which is less than the nation's reported resistance by 0.3%. United States has seen a 0.3% decline in CRE resistance from 2018 to 2019.

In 2019, the United States had a population of 328 million people, with a median age of 38.5 and a median household income of $65,712. The five largest ethnic groups in the United States are White, Black or African American, Asian, Other Ethnic Group, and American Indian or Alaska Native.

The CDC provides data on reporting general acute care, long term acute care, inpatient rehabilitation facilities, and critical access hospitals by state through the National Healthcare Safety Network (NHSN). Note: Data on critical access hospitals are currently included within general acute care hospital reporting among NHSN's Antibiotic Resistance and Hospital Antibiotic Stewardship modules represented in the AR & Patient Safety Portal.


328 million

Median Age

38.5 Years

Median Household Income


State Health Insurance


Private Healthcare Insurance


Is White
236,475,401 (72%)
Is Black Or African American
41,989,671 (12.8%)
Is Asian
18,636,984 (5.7%)
Is Other Race
16,352,553 (5%)
Is American Indian Or Alaska Native
2,847,336 (0.9%)
Is Native Hawaiian Or Other Pacific Islander
628,683 (0.2%)

Source: U.S. Census Bureau, 2019

Number of Facilities Reporting
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General Acute Care Hospitals
Long Term Acute Care Hospitals
Impatient Rehabilitation Facilities
Critical Access Hospitals

Source: NHSN, 2020


Hospital-Associated Infections

  • All HAI data provided on this page is maintained by the CDC's National Healthcare Safety Network (NHSN)
  • HAIs on this page include Central Line-Associated Bloodstream Infection (CLABSI), Catheter-Associated Urinary Tract Infection (CAUTI), Surgical Site Infections (SSI), Clostridioides difficile (C. difficile) infections, MRSA Bacteremia, and Ventilator-Associated Events (VAE).
  • Data are only displayed for U.S. states/territories for which at least 5 facilities reported an HAI in the given survey year.
  • Map legends are classified using the Jenks Natural Breaks method.
  • See the Current HAI Progress Report Technical Appendix for the full methodology and details about the data. Past HAI Progress Reports are described in the Data Archive.
  • HAI information available in the Patient Safety Portal include data from 2015 to 2019.

Antibiotic Resistance

  • HAIs include Catheter-Associated Urinary Tract Infection (CAUTI), Central Line-Associated Bloodstream Infection (CLABSI), Surgical Site Infection (SSI).
  • CI (Confidence Interval) - The national, regional, and state-level data included in Antibiotic Resistance information are displayed with 95% confidence intervals around the percent resistance, which were calculated using a mid-P exact test and are an indication of precision.
  • Map legends are classified using the Jenks Natural Breaks method.

Antibiotic Use

  • These data are from the IQVIA database and reflect all outpatient antibiotic prescriptions dispensed to humans from U.S. community pharmacies. These data do not include antibiotic prescriptions dispensed from federal facilities.
  • Data reflect annual rates of antibiotic prescriptions dispensed per 1,000 population, i.e. the number of antibiotic prescriptions dispensed per year for every 1,000 persons. Annual rates allow for comparisons of the number of antibiotic prescriptions dispensed in different geographic areas or over time while controlling for differences in the size of the underlying population.
  • Map legends are classified using the Jenks Natural Breaks method.
  • Due to missing data, totals by age group and/or sex may not add up to all prescriptions. Antibiotic class defines a set of related antibiotics. State-level rates of penicillins, macrolides, cephalosporins, and fluoroquinolones are displayed. Also displayed are all antibiotic classes, which include these four classes plus additional classes not available for release at the state level.
  • Data are not available for geographic regions smaller than states.

Hospital Antibiotic Stewardship

  • Although the vast majority of hospitals in the United States participate in NHSN, the antibiotic stewardship data summarized in this Portal may not be representative of all acute care hospitals in the United States. Also, because participation in NHSN varies by state and by year, caution should be used when making direct comparisons of uptake of core elements between states and across years.
  • Map legends are classified using the Jenks Natural Breaks method.