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CDC

Antibiotic Use

Outpatient Antibiotic Use: Pharmacy Prescriptions Dispensed to Medicare Part D Beneficiaries

Total Outpatient Antibiotic Prescriptions

69M

Total Medicare Part D antibiotic prescriptions dispensed in 2023

Outpatient Antibiotic Prescription Rate

1,343

Prescriptions per 1,000 Medicare Part D beneficiaries in 2023

Prescriber Specialty with Highest Proportion of Antibiotic Prescriptions, 2023

19%

Nurse Practitioner

Outpatient Antibiotic Use: Pharmacy Prescriptions Dispensed to Medicare Part D Beneficiaries

Population and Data

Outpatient antibiotic prescribing can be tracked through publicly available data from the Centers for Medicare & Medicaid Services (CMS). The population eligible for Medicare Part D enrollment includes adults ages ≥65 years and adults ages <65 years with qualifying disabilities (13-16%).

Geographic Locations

Antibiotics are prescribed differently across the United States. Reasons for geographic variability may include different prescribing behavior, disease burden, co-morbid conditions, diagnostic testing, and levels of antimicrobial resistance among certain pathogens.

Outpatient Antibiotic Prescription Rates for Medicare Part D Beneficiaries by State

This map displays antibiotic prescription rates per 1,000 Medicare Part D beneficiaries across U.S. states by antibiotic class and year.

Download expanded data set here.

Data source: Medicare Part D Prescribers – by Geography and Drug; CMS Program Statistics - Medicare Part D Enrollment

Outpatient Rates by State, 2023 and All Classes

Outpatient Antibiotic Prescription Rates for Medicare Part D Beneficiaries by Region

This map displays antibiotic prescription rates per 1,000 Medicare Part D beneficiaries dispensed in pharmacies across U.S. regions by antibiotic class and year.

Download expanded data set here.

Data source: Medicare Part D Prescribers – by Geography and Drug; CMS Program Statistics - Medicare Part D Enrollment

Outpatient Rates by Region, 2023 and All Classes

Changes Over Time

Antibiotic prescribing patterns may vary over time.

Changes Over Time in Outpatient Antibiotic Prescription Rates by Antibiotic Class and State

This graph displays prescriptions by antibiotic classes dispensed per 1,000 Medicare Part D beneficiaries in U.S. outpatient pharmacies from 2017–2023.

Download expanded data set here.

Data source: Medicare Part D Prescribers – by Geography and Drug; CMS Program Statistics - Medicare Part D Enrollment

All Classes Prescribing Rate, All States

Prescriber Specialty

Outpatient antibiotic prescription rates vary by prescriber specialty. Engaging prescribers by specialty provides an opportunity to optimize prescribing practices and improve quality of care.

Percentage of Antibiotic Prescriptions by Prescriber Specialty, Year and State

This graph displays the percentage of outpatient antibiotic prescriptions by prescriber specialty, year, and state. Prescriber specialty is identified in the dataset by the prescriber's National Provider Identifier (NPI).

Download expanded data set here.

Data source: Medicare Part D Prescribers - by Provider

Prescription Percentages by Prescriber Specialty, All States 2023

Footnotes

  • These data are from the Centers for Medicaid and Medicare Services (CMS) Part D Public Use Files (PUF) database and reflect outpatient antibiotic prescriptions dispensed for Medicare Part D beneficiaries from U.S. pharmacies. All outpatient antibiotic prescriptions exclude the following types of products: tuberculosis agents, antimalarials, topical agents (topical ophthalmic, optic, vaginal, and dermatological agents, etc.).
  • Three CMS PUFs are used for these analyses. The numerator for prescribing rates use the Medicare Part D Prescribers by Geography and Drug dataset and include only oral antibiotic prescriptions. The denominator for prescribing rates is obtained from the CMS Program Statistics - Medicare Part D Enrollment. The percentage of prescriptions by provider specialty is calculated from the Medicare Part D Prescribers - by Provider dataset and include all outpatient antibiotic prescriptions (not limited to oral antibiotic prescriptions).
  • Data reflect annual rates of antibiotic prescriptions dispensed per 1,000 Medicare Part D beneficiaries, i.e. the number of antibiotic prescriptions dispensed per year for every 1,000 beneficiaries in the Medicare Part D plan. Annual rates allow for comparisons of the number of antibiotic prescriptions dispensed in different geographic areas or over time while controlling for differences in the size of the underlying enrolled population.
  • Part D Prescribers data does not include drugs with fewer than 11 Part D drug claims. There may be underestimation due to potential suppression of any claim or beneficiary counts between 1 and 10.
  • Data are not available for geographic regions smaller than states.
  • Antibiotic class defines a set of related antibiotics. State-level rates of penicillins, fluoroquinolones, cephalosporins, macrolides, beta-lactams with increased activity (e.g. amoxicillin-clavulanate), tetracyclines, trimethoprim-sulfamethoxazole, lincosamides (e.g. clindamycin), urinary anti-infectives, and other antibiotics are displayed.